PATHOGENIC FREE-LIVING AMOEBA

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Pathogenic Free-living Amoeba

These are Acanthamoeba spp., Balamuthia mandrillaris (the only known species of Balamuthia), Naegleria fowleri (sometimes considered not to be an amoeba at all, but more closely related to Leishmania and Trypanosoma) and Sappinia pedata. They are distinct from the more famous Entamoeba histolytica (an obligate anaerobic parasite which can cause amoebiasis, amoebic dysentery and amoebic liver ab...

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Detection of Potentially Pathogenic Free-living Amoeba, from the Internal Environment of Educational Hospitals in Rasht

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Apoptosis as a mechanism of cytolysis of tumor cells by a pathogenic free-living amoeba.

Previous studies have shown that trophozoites of the pathogenic free-living amoeba Acanthamoeba castellanii rapidly lysed a variety of tumor cells in vitro. Tumor cells undergoing parasite-mediated lysis displayed characteristic cell membrane blebbing reminiscent of apoptosis. The present investigation examined the role of apoptosis (programmed cell death) in Acanthamoeba-mediated tumor cell ly...

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In vitro and in vivo tumoricidal properties of a pathogenic/free-living amoeba.

The chemotactic and tumoricidal properties of the pathogenic/free-living amoeba Acanthamoeba castellanii were examined in vivo and in vitro. A. castellanii trophozoites displayed strong positive chemotactic responses to human melanoma (OCM-1) and murine melanoma (D5.1G4) cells. Although the parasites typically invade and destroy the corneal epithelium and stroma, positive chemotactic responses ...

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The role of free-living pathogenic amoeba in the transmission of leprosy: a proof of principle.

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ژورنال

عنوان ژورنال: Postępy Mikrobiologii - Advancements of Microbiology

سال: 2019

ISSN: 0079-4252,2545-3149

DOI: 10.21307/pm-2017.56.1.106